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paper 5 September 2025

Publication: PACIFIC maps synergistic interactions in cancer multi-omics data

Congratulations to Masroor Bayati on his publication “Cancer genomic alterations and microenvironmental features encode synergistic interactions with disease outcomes” in Molecular Cancer Research. Masroor and colleagues developed PACIFIC, an open-source method that maps synergistic, clinically informative interactions in cancer multi-omics data, and used it to find combinations of genomic driver alterations and tumour microenvironment features that jointly associate with patient prognosis in several cancer types.