Reimand Lab July 2017

Current Lab members

juri-01 Jüri Reimand – principal investigator

I am an investigator of informatics and biocomputing at the Ontario Institute of Cancer Research. I also have a faculty appointment of assistant professor at the University of Toronto with the department of Medical Biophysics. I completed my PhD in computer science at the University of Tartu in Estonia in 2010 and my postdoctoral training at the Donnelly Centre of the University of Toronto during 2011-2015. I joined the OICR in summer of 2015 and started my lab shortly after. I am interested in computational biology and cancer research, in particular integrative and network-driven approaches to interpret genomic information and advance our understanding of cancer biology and treatment.

lina-01 Lina Wadi – staff bioinformatician

I did my undergraduate degree in Molecular Biology & Genetics at the University of Guelph and was introduced to Bioinformatics in one of my upper year courses. I was really interested in the possibility to use computer techniques to address biological questions and so I enrolled in the coursework Bioinformatics masters program at the University of Guelph were I completed a project involving two of my interests: cancer biology and bioinformatics. Since completing school in 2014, I have been working at the OICR where I am analyzing cancer datasets using computational methods. My recent projects involve prognostic biomarker discovery in breast cancer as well as pathway analyses to understand the underlying biology and generate new hypotheses in various cancer types.

luyao-01 Luyao Ruan – co-op biostatistician

I am a master student at the University of Waterloo, major in Statistics. My interest of study lies in machine learning and classification. R is my major programming language. Currently I am working on a project of classifying motif binding and mutations of DNA sequence.

michal-01 Michal Krassowski – software engineer 

I am an undergraduate student at the University of Warsaw in field of Bioinformatics and Systems Biology, with a solid background in informatics. I work here on the project called “Interactive visualisation framework for genome mutations in gene and protein networks” where I develop a website displaying different visualizations that are useful for researchers studying e.g. effects of mutations on protein-protein interactions and signalling. The project is supported by Google Summer Code and mentored by Jüri Reimand.

marta-01 Marta Paczkowska – junior bioinformatician

I have just received my master’s degree in Bioinformatics and Systems Biology at the University of Warsaw (Poland). During my studies I had the opportunity to gain knowledge in the fields of computer science and molecular biology.  My major interest lies in cancer research. Currently I am working on modelling protein-peptide interactions and pathway analysis.

Karina Isaev – graduate student

I am a master’s student with the Department of Medical Biophysics at the University of Toronto. I am interested in elucidating the functions of long non-coding RNAs (lncRNAs) which are emerging as potential regulators of important processes in cancer. Currently there are over 19,000 annotated lncRNA genes where only a small subset has been functionally described. Using integrative pan-cancer data from projects such as PCAWG and TCGA, I would like to identify key pathways that lncRNAs are implicated in in order to predict their functions.

Yao Li – co-op biostatistician

I am a master’s student in Biostatistics program, Department of Statistics and Actuarial Science, at the University of Waterloo. My research interest is about causal inference using machine learning methods. I am currently working on analyzing gene co-expression networks.

Drew Thompson – co-op student

I am an undergraduate student at the University of Waterloo in the Computer Science – Bioinformatics Option program where I take courses in the fields of computer science, bioinformatics, and biology. I am interested in molecular biology and its intersection with computer science, and the implications this has for research and healthcare.

Tina Huang – summer student

I am a recent H.B.Sc graduate from the University of Toronto with a specialist in pharmacology. My research interests lie in the use of computational biology approaches for cancer research, particularly in the domain of pharmacogenomics. My current project involves analyzing somatic mutations in cancer genomes for potential kinase rewiring events.

Irakli Dzneladze – visiting researcher

I received my PhD at the Department of Medical Biophysics at the University of Toronto/Princess Margaret Cancer Center. Prior to that, I received an BSc degree in biochemistry from York University, with a honors thesis project in immunology. Overall, my research background is in experimental biology, with a primary focus on biochemistry, and cell and molecular biology. However, throughout my doctoral research I had a strong interest in bioinformatics, which I was able to pursue in the second half of my PhD. Combining bioinformatics and experimental biology, I was able to identify a gene whose expression status is associated with poor clinical outcome in acute myeloid leukemia (AML), and conduct experimental examination of its deregulated expression in AML cell lines. My current research interest is in biomarker discovery, and validation.



2015-2016 Mona Meyer – postdoctoral cell biologist
Nov 2015 Hui Guo – rotation student
July-Sept 2015 Carla Rossell – summer student
May-Sept 2015 Noman Siddiqui – co-op software engineer

Celebrating year one, July 2016