ActiveDriverDB paper published in NAR

Our database of disease mutations in protein signalling sites is now published in the 2018 Database Issue of Nucleic Acids Research (Krassowski et al). This effort is led by Michal Krassowski and was initiated by a Google Summer of Code project two years ago.

The database contains hundreds of thousands of genome variants that affect protein signalling sites of post-translational modifications. Using this information in a comprehensive way, we can predict functions of genome variation and disease mutations on protein signalling networks.

The database is available at and provides visual browsing, application programming interfaces and data analysis of custom uploaded datasets.